amygdala1_enlarged-6582717

IMFAR 2011: Neuropathology of the Amygdala in Autism

C. M. Schumann, UC Davis MIND Institute The following is a modified transcription of Ms Schumann’s talk. Any glaring omissions or errors are my own. INSAR members can listen to Ms Schumann’s talk in its entirety via the abstract page. -SR The amygdala is enlarged in children with autism, and this has been a consistent finding, in several studies. By 2.5 years of age, the amygdala is enlarged in children with autism by about six percent. Longitudinal studies show that amygdala enlargement continues to increase — by four years of age, there is a nine percent enlargement, compared to controls. What’s interesting is that the total brain volume is larger in children with autism in this age range, but that volume is not necessarily rapidly growing during this time — it’s staying fairly consistent, and not necessarily growing faster as the amygdala is. The growth pattern doesn’t occur in all…