IMFAR 2012: Genetic Variants in ASD

Any omissions or errors in this summary are on TPGA; we have tried to include explanatory links for specific scientific terms. -SR Common and Genetic Variants in the Etiology of ASD: Where is the Field Heading? Bernie Devlin University of Pittsburgh Statistical geneticist, helps design projects & studies. Dr. Devlin’s goal: convince you that we know quite a bit about the genetics of autism, in a few years we’ll know more. Exciting times! Are those times going to continue? Devlin maintains, yes.     Using array-based tech & high throughput sequencing,     Samples and collaboration He considers that discovery of autism risk genes is going to increase exponentially in near future. How will we get there? Autism Genome Project (AGP) Trios: Mother, Father, ASD child Families could be multiplex (2+ ASD individuals per family) or simplex (1 ASD individual per family)     Simons Simplex Collection (SSC) Families are mostly quartets (Mother,…